Minoxidil CAS 38304-91-5 Hair Loss Treatment Pure Minoxidil 98% Powder
Basic Info.
Product Name:Minoxidil
CAS: 38304-91-5
Molecular Weight: 209.2483
Formula: C9H15N5O
Melting point : 258-262
Content : ≥ 99%
Specifications: 25KG / drum
Properties: The product is white or almost white crystalline powder. Dissolved in glacial acetic acid , slightly soluble in ethanol , slightly soluble in chloroform or water , very slightly soluble in acetone.
Description:
Minoxidil is an antihypertensive vasodilator medication also claiming to slow or stop hair loss and promote hair regrowth. It is available over the counter for treatment of androgenic alopecia, among other baldness treatments, but measurable changes, if experienced, disappear within months after discontinuation of treatment.
Minoxidil was first sold as a drug for high blood pressure and was noted to have the interesting side-effect of increased body hair-growth, or in some cases, significant hair loss. Treatments for baldness and hair loss usually include a 5% concentration solution that is designed for men, whereas the 2% concentration solutions are designed for women. Minoxidil, applied topically, is widely used for the treatment of hair loss. It is effective in helping promote hair growth in both males and females with androgenic alopecia.About 40% of men experience hair regrowth after 3-6 months.Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth.It is the only topical product that is FDA-approved for androgenic hair loss.Treatments usually include a 5% concentration solution that is designed for men, and a 2% concentration solution for women.Minoxidil has been approved for female use by the FDA.
Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness. In the 1980s, UpJohn Corporation came out with a topical solution of 2% minoxidil, called Rogaine, for the specific treatment of androgenetic alopecia. Since the 1990s, numerous generic forms of minoxidil have become available to treat hair loss while the oral form is still used to treat high blood pressure. Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. It is available over the counter for treatment of androgenic alopecia, among other baldness treatments, but measurable changes disappear within months after discontinuation of treatment. Its effectiveness has largely been demonstrated in younger men (18 to 41 years of age), the younger the better, and in those with balding in the central (vertex) portion of the scalp. Minoxidil is a potassium channel agonist. It contains the chemical structure of nitric oxide), a blood vessel dilator, and may be a nitric oxide agonist. This appears to explain its vasodilatory effects, but may also be linked to minoxidil’s ability to stimulate hair growth and treat hair loss. Since minoxidil is a nitric oxide-related compound, it was suspected to act via activation of guanylate cyclase, an enzyme involved in vasodilation.
Certificate of Analysis
Item |
Specification |
Result |
Assay |
98% |
98.20% |
Appearance |
White powder |
conforms |
Odor |
Characteristic |
conforms |
Taste |
Characteristic |
conforms |
Particle Size |
NLT 100% Through 80 mesh |
conforms |
Loss on Drying |
<2.0% |
0.46% |
Heavy metals |
Total Heavy Metals |
≤10ppm |
conforms |
Arsenic |
≤3ppm |
conforms |
Lead |
≤3ppm |
conforms |
Microbiological Tests |
Total Plate Count |
≤1000cfu/g |
conforms |
Total Yeast & Mold |
≤100cfu/g |
conforms |
E.Coli |
Negative |
Negative |
Salmonella |
Negative |
Negative |