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  • Nootropic SARM Steroids Powder Coluracetam BCI – 540 CAS 135463-81-9

    CATEGORY AND TAGS:
    Other Hot-Sale Products (Raw Powder)
    Model Number : 135463-81-9
    Certification : ISO 9001, USP,GMP
    Place of Origin : China
    MOQ : negotiation
    Price : negotiation
    Payment Terms : Western Union, MoneyGram, T/T, bitcoin
    Supply Ability : Mass in stock
    Delivery Time : 3-5 work days
    Packaging Details : Disguised package ; Foil bag
    Name : Coluracetam
    CAS : 135463-81-9
    Grade : Pharmaceutical
    Package : Well disguised package ;Foil bag
    Purity : 98%
    Appearance : white powder
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    • Specifications

    Nootropic SARM Steroids Powder Coluracetam BCI – 540 CAS 135463-81-9

    What is Coluracetam?

    Coluracetam, as known as MKC-231 has been classed as a nootropic agent. It’s known to enhance cognitive effects, based on the ways in which it influences choline uptake. Originally developed to treat Alzheimer’s disease, Coluracetam was found to be more effective as a nootropic and is purely marketed as a cognitive enhancer.

    It is one of the newer racetam nootropics to reach the market. Since Coluracetam enhances levels of choline in the brain and body, it increases the production of acetylcholine. Without acetylcholine, we wouldn’t be able to remember the simplest of facts or move our muscles. It’s been reported that Coluracetam not only increases acetylcholine levels but also speeds up its flow.

    Quick Detail

    Product Name Coluracetam / MKC-231
    Assay 98%Min
    CAS Registered No. 135463-81-9
    Molecular Formula C19H23N3O3
    Molecular Weight 341.4042
    Appearance White Powder
    Trademark Pharmlab
    Packing Method 1kg/Aluminum Foil Bag or as Your Requirement
    Standard USP;ISO9001
    Origin China
    Export Markets Global
    Usage Gain muscle and lean mass
    Storage keep cool and dry, away from light
    Payment Terms Western Union, MoneyGram, Wire Transfer, Bitcoin
    Delivery Time Within 24hours After Payment
    Shipping Method EMS, DHL, FedEx, TNT, Express Courier.
    Chemical structure  

    Description

    Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer’s disease.

    Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown

    Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.

    Application

    Memory and Learning

    Coluracetam is shown to improve cognitive function and memory in rats, and in theory, the same results are expected in human beings. A study conducted by BrainCells Inc, showed a memory improvement in rats who were given substance AF64A (a neuron-specific neurotoxin) for 8 days along with Coluracetam in 3mg doses. These rats were put through the standardized Morris Water Maze to mark their ability to get through it, and even up to 72 hours after the last 8mg dose, they were still able to. Another key finding of this study was that the results were still apparent 3 days after the last dose, even though the serum concentration of Coluracetam was negligible.

    Depression and Anxiety

    BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in treating major depression co-morbid with GAD (generalized anxiety disorder). However, the differences were most pronounced in those who didn’t find relief in using standard antidepressants. After one dose, there were no noticeable differences, but after 2 doses at 80mg, 36% had improved scores during a depression assessment test.

    Eyesight

    Coluracetam has been associated with optic benefits such as enhanced color vision, recognition and vividness. Although there isn’t any conclusive evidence to support the mechanisms behind this benefit, experts believe that Coluracetam works in the part of the brain that runs visual processes.

    COA of Coluracetam/ MKC-231 Powder

    Analysis Test Specification Result
    Description White crystalline powder, odorless Conform
    Solubility Easily soluble in water, unsoluble in ethanol Conform
    PH 6.0~7.5 6.9
    Solution clarity and color Solution should be clear and colorless Conform
    Related substances 5’CMP 0.3%
    Simple impurity
    Total other impurity
    0.01%
    0.03%
    0.10%
    Chloride 0.05% Conform
    Ammonium 0.05% Conform
    Fe 0.01% Conform
    Phosphate 0.1% Conform
    Loss on drying ≤6.0% 1.3%
    Heavy metals 0.002% Conform
    Arsenide 0.0001% Conform
    Bacterial Endotoxins 0.3EU/mg Conform
    Microbial Limit Conform Conform
    Assay (on dried basis) ≥99.0%

    Coluracetam DOSING

    Since the study subjects were mainly rats, there isn’t any recommended human dosages, but there is a general guideline for conversion.

    In rats, the dosage ranged between 1 mg/kg and 10 mg/kg per day. By using allometric scaling, the dose becomes 2.9 mg/kg in humans, so the average dose should not exceed 203.5 mg daily for someone in a typical weight class.

    There isn’t very much information to indicate toxicity of Coluracetam, although doses given at the above increments showed no negative side effects. If you haven’t used a nootropic before, you may develop headache after use, which is a common in first time users. By stacking the Coluracetam with Choline, you’ll reduce this risk.

    Coluracetam Functions

    1. Enhance mental intelligence
    2. Boost memory and leaning capabilities
    3. Improve brain power to solve problems and protect it from any chemical or physical injury
    4. Enhance motivation level
    5. Enhance the control of cortical/subcortical brain mechanism
    6. Improve sensory perception    

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    Competitive Advantage

    1. Our company is a professional production leading factory in China in pharmaceutical area of many years.

    Delivery areas of our products: US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.

    Payment method: T/T, Western union, Moneygram, bitcoin etc.

    2. Discreet package. The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.

    3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.

    4. Security Shipping: Shipping by express (FedEx, UPS, DHL, EMS), by air. The most professional forwarder would be recommanded for you.

    5. We have stock, so we can delivery quickly at the very day when receive the payment.

    6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.

    7. A discount would be given when you make a large order.

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