99.8 % Pharmaceutical Grade Raw Materials Promethazine HCL
Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.
Product Details:
Product Name |
Promethazine hydrochlorine |
Other Name |
Promethazine HCl |
Chemcial Name |
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine |
CAS |
58-33-3 |
MF |
C17H21ClN2S |
MW |
320.88 |
EINECS |
200-375-2 |
Assay |
99.8% |
Appearence |
White powder |
urpose |
This product is used for skin and mucosa irritation, allergic rhinitis,
asthma, food allergies, skin scratch disease, motion sickness, airsickness etc.. |
Description:
Promethazine hydrochloride is a phenothiazine used to treat or prevent nausea and vomiting caused by anesthesia or surgery, certain types of allergic reactions, pain caused by surgery or childbirth, and to sedate patients before surgery or medical procedures. Promethazine injection is usually given when a person cannot take the medication orally (by mouth). Promethazine hydrochloride is available in generic form. Promethazine hydrochloride suppositories (Brand Names: Phenadoz, Promethegan) is a phenothiazine that works by changing the actions of chemicals in your brain, and also acts as an antihistamine, used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. Promethazine hydrochloride suppositories is also used to prevent motion sickness, treat nausea and vomiting or pain after surgery, and as a sedative or sleep aid. Promethazine hydrochloride suppositories are available in generic form. Common side effects of promethazine hydrochloride suppositories include dizziness, drowsiness, sleepiness, restlessness, blurred vision, dry mouth, stuffy nose, ringing in the ears, weight gain, swelling in hands or feet, impotence, trouble having an orgasm, or constipation.
Application:
Antihistaminic, antiemetic, CNS depressant stool softener With aminophylline in the treatment of asthma For the treatment of allergic disorders, and nausea/vomiting.
Dubbed hibernation and injection for artificial hibernation. Perennial and seasonal allergic rhinitis Vasomotor rhinitis.Allergic conjunctivitis due to inhalant allergens and foods.Mild, uncomplicated allergic skin manifestations of urticaria and angioedema.
Amelioration of allergic reactions to blood or plasma. Dermographism. Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled. Preoperative, postoperative, or obstetric sedation. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. Therapy adjunctive to meperidine or other analgesics for control of postoperative pain. Sedation in both children and adults, as well as relief of apprehension and production of light sleep from which the patient can be easily aroused. Active and prophylactic treatment of motion sickness. Antiemetic therapy in postoperative patients.
The dose of promethazine depends on the condition being treated. Typical doses range from 12.5 mg to 25 mg, and may be taken once daily or several times per day, as prescribed. Promethazine may interact with cold or allergy medicine, sedatives, narcotics, sleeping pills, muscle relaxers, medicine for seizures, depression, lithium, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, blood pressure medications, blood thinners, bronchodilators, bladder or urinary medications, MAO inhibitors, medicines to treat Parkinson’s disease, restless leg syndrome, or pituitary gland tumor, medicines to treat stomach ulcer or irritable bowel syndrome. Many other medicines can interact with promethazine. Tell your doctor all medications and supplements you use. During pregnancy, promethazine should be used only if prescribed. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
COA:
Items of analysis |
Specification |
Results |
description |
a white or faintly yellowish,crystalline powder |
a white crystalline powder |
solubility |
very soluble in water,freely soluble in chloroform and in ethanol(95%),practically insoluble in ether |
very soluble in water,freely soluble in chloroform and in ethanol(95%);practically insoluble in ether |
identification |
|
|
A. IR absorption spectrum |
the positions and relative sizes of the banks in the spectrum of the sample and reference spectrum shall be concordant |
the positions and relative sizes of the bands in the spectrum of the sample and reference spectrum are concordant |
B.by TLC |
It complies with the identification test for phenothiazines |
it complies with the identification test for phenothiazine |
C.Test with nitric acid |
forms orange colored solution and organge-red precipitate |
forms orange colored solution and organge-red precipitate |
D.test for chlorides |
shall comply the test |
complies with test for chlorides |
pH(10% w/v solution) |
4.0-5.0 |
4.31 |
related substances(by TLC) |
|
|
isopromethazine |
not more than 1.0% |
less than 1.0% |
other impurity |
not more than 0.5% |
less than 0.5% |
sulphated ash |
not more than 0.5% |
0.20% |
loss on drying at 105ºC |
not more than 0.5% |
0.20% |
assay(by potentiometric titration) |
98.5-101%(on anhydrous basis) |
100.0% |
Conclusion |
Qualified |
Our service
1.100% reshipment policy is our business basic.100% reshipment immediately if your parcel stays Customs for 4 days and doesn’t get updated.
2.Total refund for 15 days of dissatisfaction with quality.
3.We can provide free samples.
4.We have a special packing ,It can be easily passed through the customs.It will be more safe.
5.Our company have a long term cooperate with DHL.EMS.Fedex and so on .It can be sent to your hand more quickly. Parcel photo should be offered within 12hours after receiving your steroid payment.
6.If you have a chance to come to China. I can show you our lab.
7.Our company has WU, MG, TT, and Bitcoin payment ways in advance.You can pay 95% for the peptides cost at first for order, the rest can offer us in your next order;
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