99% Purity Nootropics Supplement Powder Prl-8-53 HCl CAS 51352-87-5
Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.
Product Details:
| Product Name |
PRL-8-53 HCL |
| Alias |
Prl-8-53 HCL |
| CAS |
51352-87-5 |
| MF |
C18H22ClNO2 |
| MW |
319.82578 |
| Purity |
99.50% |
| Grade |
Pharmaceutical Grade |
| Appearance |
white crystalline powder. |
| Standard |
USP |
| Stock |
Mass Stock |
| Usage |
PRL-8-53 HCL improves brain circulation |
Description:
PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%. The single study involving humans showed PRL-8-53 improved word recollection scores both 24 and 96 hours after initial memorization. Given the low amount of evidence available for this nootropic, we thought it relevant to reference a journal article in which the creator discusses the compound and numerous other human trials it was used in.
Application:
PRL-8-53’s exact mechanisms of action are not well understood, but it is generally believed to regulate the brain’s production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain’s response to acetylcholine.
Though Hansl’s research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53’s effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.
COA:
| Item |
Inspection Standard |
Results |
| Appearance |
Off white solid powder |
Conform |
| Identification |
Conform with NMR |
Conforms |
| Melting Point |
149-152°C |
150-151°C |
| Loss on Drying |
≤0.50% |
0.21% |
| Residue on ignition |
≤1.0% |
0.32% |
| Purity(HPLC) |
≥99% |
99.2% |
| Heavy metals |
NMT 20PPM |
Conforms |
| Conclusion:This product by inspection accords with the in-house standard |
Benefits:
It is generally considered to be a memory and learning enhancer. In the lone study with rats, taking PRL-8-53 120 – 150 minutes before a cognitive test helped drastically. Memory was tested at 24 hours after dosing and 96 hours with positive results compared to a placebo. Within these tests, some of the test performance improvements were in the range of 80 – 100+%, which suggests significant potential. The study separated the analysis of memory and “working memory”, which showed less improvement, but still notable.
Dossage:
More evidence is needed to determine the ideal dosage for PRL-8-53. The effective dosage may vary, since the only human study on PRL-8-53 used a single dose of 5mg, while patent information on PRL-8-53 suggests a dosage range of 0.01-4mg/kg, with an ‘ideal’ range of 0.05-1.2mg/kg.
Our service
1.100% reshipment policy is our business basic.100% reshipment immediately if your parcel stays Customs for 4 days and doesn’t get updated.
2.Total refund for 15 days of dissatisfaction with quality.
3.We can provide free samples.
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5.Our company have a long term cooperate with DHL.EMS.Fedex and so on .It can be sent to your hand more quickly. Parcel photo should be offered within 12hours after receiving your steroid payment.
6.If you have a chance to come to China. I can show you our lab.
7.Our company has WU, MG, TT, and Bitcoin payment ways in advance.You can pay 95% for the peptides cost at first for order, the rest can offer us in your next order;
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