99.6% Purity Gonadorelin with High Quality
Product Description
Name:Gonadorelin
Sequence: Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Product Categories:Amino Acid Derivatives;Peptide;API;peptides
Molecular For White powdermula: C59H83N17O17
Single Impurity (HPLC): 0.5%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤8.0%
Acetate Content(HPIC): ≤10.0%
Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)
Mass Balance: 95.0~105.0%
What is Gonadorelin ?
Gonadorelin is another name for gonadorelin releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.
GnRH is available as gonadorelin hydrochloride and gonadorelin diacetate tetrahydrate for injectable use. infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
.Application
Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.
Uses
Gonadorelin is used by women who are missing menstrual periods due to low levels of releasing hormone (GnRH). It may be used as part of female infertility treatment. This medication provides GnRH that the body needs for the growth and release of mature eggs from the ovaries (ovulation).
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