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  • 53179-13-8 Pharmaceutical Active Ingredients Powder Antineoplastic Pirfenidone

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    Other Hot-Sale Products (Raw Powder)
    Model Number : 53179-13-8
    Certification : ISO 9001, USP,GMP
    Place of Origin : China
    MOQ : 10g
    Price : negotiation
    Payment Terms : Western Union, MoneyGram, T/T, bitcoin
    Supply Ability : Mass in stock
    Delivery Time : 3-5 work days
    Packaging Details : Disguised package ; Foil bag
    Product name : Pirfenidone
    Other name : Arm-69
    CAS : 53179-13-8
    appearance : Off-White Solid
    purity : 99%
    MF : C12H11NO
    MW : 185.22
    Policy : Re-Shipping Policy
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    • Specifications

    53179-13-8 Pharmaceutical Active Ingredients Powder Antineoplastic Pirfenidone

    Quick detail

    Product name: Pirfenidone

    Other name: Arm-69

    CAS: 53179-13-8

    appearance: Off-White Solid

    purity: 99%

    Trademark: Pharmlab

    Original: China

    Grade: Pharmaceutical grade

    Package: Disguised package ; Foil bag

    Delivery date: 3-5 work days

    Certificate: ISO 9001, USP,GMP

    Payment: Western Union, MoneyGram, T/T, bitcoin

    Shipping: EMS,HKEMS,EUB,ETK,FEDEX,DHL,UPS,Aramex,ETC

    Policy: Re-Shipping Policy

    MF: C12H11NO

    MW: 185.22

    mp: 96-97°C

    storage temp: Store at RT

    solubility DMSO: ≥10 mg/mL, soluble

    COA

    HP9012 Pirfenidone Assay: 98.5%~101.0% CAS53179-13-8 Fresh stock

    Pirfenidone CAS 53179-13-8 Brand: Network Union
    MW: 185.22 MSDS: Avaiable
    MF : C12H11NO Sample: Avaiable
    Category:Antiinflammatory Agents Min order: 10grams
    Quality standard : Enterprise standard Place of Origin:China
    Introduction Uses: The new anti-fibrotic material, with broad-spectrum anti-lung, liver, kidney, heart, and peritoneal fibrosis
    Character White powder
    Applications Pharmaceutical raw materials

    product description

    In vitro, pirfenidone can inhibit the proliferation of uterine leiomyoma cells and leiomyoma cells. Pirfenidone inhibits the formation of collagen in TGF-β-1-induced fibroblasts. Inhibition of PDGF, FGF and TGF-β-1 induced fibroblast proliferation. In the hamster model, pirfenidone, orally, prevents and treat bleomycin-induced pulmonary fibrosis. Pirfenidone can prevent chemically induced rat sclerosing peritonitis and can also be treated with keloid transplantation for nude mice.

    Pirrenidone 0.01 1 mg / ml can inhibit the matrix and dose-dependent manner of serum stimulation of uterine fibroids and leiomyoma cell DNA synthesis, the compound without cytotoxicity, the collagen mRNA levels have no effect. Pirfenidone in the hamster pulmonary fibrosis model can reduce the level of collagen I mRNA levels before the disease, reduce lung proline levels and malondialdehyde and lung preservation of amino acid hydroxylase activity.

    Product Application

    Pirfenidone is an antiinflammatory drug used to treat idiopathic pulmonary fibrosis. Anti-fibrosis agents, effective lung and pulmonary fibrosis models. Inhibit collagen production and fibroblast proliferation. Regulate the level of cytokines after oral administration of the body. Free radical scavengers and lipid peroxidation inhibitors. Pirfenidone inhibits collagen production and fibroblast proliferation. Antibacterial and antiinflammatory properties have been shown in various pulmonary fibrosis animal models and in clinical trials.

    How to use pirfenidone

    Use pirfenidone in accordance with the doctor’s instructions. Check whether the label on the drug has an accurate dose description.Phenylethanone can provide additional patient leaflets. If you have any questions about this information, please contact your pharmacist.Palladium with food orally.If you take pirfenidone at the same time every day, the best effect.If you miss a dose of pirfenidone, put it as soon as possible. If your next dose is almost time, skip the missed dose and return to your regular dosing regimen. Do not take 2 doses at a time.If you miss the 14-day or more days of pirfenidone, call your doctor to understand how to handle it.For questions about how to use pirfenidone, consult your health care provider.

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