135463-81-9 Coluracetam /MKC-231 for Brain Improve Nootropics

135463-81-9 Coluracetam /MKC-231 for Brain Improve Nootropics

Zhongshan Latterson Biotechnology Co., Ltd. is a large hight tech chemical enterprise which specialized in fine chemicals, pharmaceutical raw material and intermediates.Company factory has passed ISO9001 quality system certification and international KOSHER certification.As the leader of steroid raw powder, injectable and oral liquids, finished products and peptides for years, HongKong Blue Universal Co., Limited. Is aim to occupy major market share of USA, Canada, UK, Brazil, Netherlands, Ireland, New Zealand, Austria, Australia, German and worldwide. Quality is our life! All products produced in Aseptic Laboratory according to GMP standard. Approved the ISO 9001: 2008 and ISO14001: 2004. Besides, we have a complete Q. A. & Q. C. System. We own authorized sets of analyzing instruments, such as HPLC, GC and UV spectrophotometer to analyze and control the products.
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What is Coluracetam (MKC-231) :

Coluracetam (MKC-231) is a synthetic Racetam drug purported to be a Nootropic compound. It does not have a large body of evidence investigating it, but the mechanisms of action (as well as structute) appear to be very distinct from other racetam compounds like Piracetam or Aniracetam.
Coluracetam appears to interact with a process known as high affinity choline uptake (HACU for short), which is the rate-limiting step of drawing choline into a neuron for synthesis into the neurotransmitter acetylcholine. Increasing the HACU rate appears to increase the activity of cholinergic neurons, so it is a desired target for cognitive enhancement.

Interventions in rats (as there is no human evidence currently) support the usage of coluracetam at very low oral doses to preserve HACU that is otherwise impaired by the use of research drugs that are known to impair HACU. The limited evidence looking at the inherent effects of coluracetam on the HACU of normal neurons has failed to find any significant interaction.
Coluracetam has also been noted to associate with choline transporters physically, but it is not known exactly what it does once associated.

Overall, there is currently insufficient evidence to support the usage of coluracetam for cognitive enhancement. Further studies are needed to see if it has a therapeutic role in instances where HACU may be impaired (such as Alzheimer’s disease).

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