Muscle Growth Use Steroid Raw Material Androsterone White Powder For Bodybuilding
Formula :C19H30O2
Number :53-41-8
Molar mass: 290.440 g/mol
MP: 181-184 °C(lit.)
Storage temp. : −20°C
Alpha : 96 º (c=1, C2H5OH)
Appearance:white to light beige crystalline powder
Usage:Antihypertensor.It was isolated from male urine after removed of the phenolic estrogen fraction
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is approximately 1/7th that of testosterone. In addition, it can be converted to dihydrotestosterone (DHT) from 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such as androstenedione and testosterone, and as such, can be considered to be a metabolic intermediate in its own right.
Androsterone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAAreceptor, and possesses anticonvulsant effects. The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone’s 3β-isomer is epiandrosterone, and its 5β-epimer is etiocholanolone.
History
It was first isolated in 1931, by Adolf Friedrich Johann Butenandt and Kurt Tscherning. They distilled over 17,000 liters (3,700 imp gal; 4,500 U.S. gal) of male urine, from which they got 50 milligrams (0.77 gr) of crystalline androsterone, which was sufficient to find that the chemical formula was very similar to estrone.
Sources
Androsterone has been shown to naturally occur in pine pollen and is well known in many animal species.
Biological role
Androsterone is generally considered to be an inactive metabolite of testosterone, which when conjugated by glucuronidation and sulfation allows testosterone to be removed from the body, but it is a weak neurosteroid that can cross into the brain and could have effects on brain function.
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