High Purity Formestane/Lentaron CAS 566-48-3 Anti Estrogen Steroids
Product Description:
Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.
Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor. It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes.
Application:
Formestan Lentaron is a drug that has been previously used in breast cancer treatment. Like most drugs which have some sort of phsyique usage, athletes eventually get a hold of it. Formestan is currently one of the best legal anti-estrogens out there. It is classified as an irreversible arromatase inhibitor, meaning, it destroys the aromatase enzyme.
COA
TEST ITEMS |
SPECIFICATION |
RESULTS |
Description |
White or Almost White Crystalline Powder |
white powder |
Identification |
A.B. |
Positive |
Assay |
97.0~103.0% |
99.3% |
Specific Rotation |
+101°~+105° |
+102.6° |
Loss On Drying |
1.0%max |
0.27% |
Melting Point |
153~157°C |
153.0~155.0°C |
Organic Volatile Impurities |
meets the requirement. |
Conforms |
Related Substances |
meets the requirement. |
Conforms |
Residual Solvents |
meets the requirement. |
Conforms |
Particle Size |
100% ≤ 20 microns |
Conforms |
Conclusion |
The specification conform with USP35 standard |