Anti Obesity Drugs Rimonabant / Rimonabant Hydrochloride CAS 158681-13-1
Product Name: Rimonabant hydrochloride
Synonyms: RIMONABANT HYDROCHLORIDE;5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-n-1-piperidinyl-1h-pyrazole-3-carboxamide monohydrochloride;ACOMPLIA;ACOMPLIA (RIMONABANT;RIMONABANT HCL;Rimonabant(Acomplia);RimonabantConsultedStandard;Acomplia, SR141716
CAS: 158681-13-1
MF: C22H21Cl3N4O.ClH
MW: 500.25
RimonabantAdverse effects
Data from clinical trials submitted to regulatory authorities showed that rimonabant caused depressive disorders or mood alterations in up to 10% of subjects and suicidal ideation in around 1%, and in Europe it was contraindicated for people with any psychiatric disorder, including depressed or suicidal people.
Additionally, nausea and upper respiratory tract infections were very common (occurring in more than 10% of people) adverse effects; common adverse effects (occurring in between 1% and 10% of people) included gastroenteritis, anxiety, irritability, insomnia and other sleep disorders, hot flushes, diarrhea, vomiting, dry or itchy skin, tendonitis, muscle cramps and spasms, fatigue, flu-like symptoms, and increased risk of falling.
The FDA’s advisory committee raised concerns that based on animal data, it appeared that the therapeutic window with regard to CNS toxicity, and specifically seizures was almost nonexistent; the therapeutic dose and the dose that caused seizures in animals appeared to be the same. When the EMA reviewed postmarketing surveillance data, it found that the risk of psychiatric disorders in people taking rimonabant was doubled.
COA:
| Product Name |
Rimonabant |
Batch No. |
170728 |
| Report Date |
2017/7/28 |
| Test Items |
Specification |
Test Results |
| Appearance |
Off white crystalline powder |
Off white crystalline powder |
| Melting Point |
233.2oC~236.1oC |
230oC~240oC |
| L.O.D |
0.23% |
≤0.5% |
| Solubility |
Conforms |
Freely soluble in methanol |
| Heavy metals(Pb) |
10ppm |
≤10ppm |
| Assay |
99.65% |
≥99.5% |
| T.L.C. |
Only one spot |
Only one spot |
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FAQ
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
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Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
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