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  • Alzheime Medicine Raw Material Rivastigmine Tartrate CAS 129101-54-8

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    Other Hot-Sale Products (Raw Powder)
    Model Number : CAS: 129101-54-8
    Certification : GMP,SGS,ISO9001:2008,KOSHER
    Place of Origin : China
    MOQ : 10g
    Price : Negotiable
    Payment Terms : Western Union, MoneyGram, Bank Transfer, Bitcoin
    Supply Ability : 3000KG/Month
    Delivery Time : Usually within 7 work days
    Packaging Details : Stealth and discreet packaging
    Product Name : Rivastigmine Tartrate
    CAS : 129101-54-8
    MF : C18H28N2O8
    MW : 400.4235
    Purity : 99%
    appearance : White Powder
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    • Specifications

    Alzheime Medicine Raw Material Rivastigmine Tartrate CAS 129101-54-8

    Superiority

    Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
    Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.

    Product Details:

    Product Name: Rivastigmine Tartrate
    Alias: Rivastigmine-d6 tartarate
    CAS: 129101-54-8
    MF: C18H28N2O8
    MW: 400.4235
    Purity: 99%
    MP: 123-125°C
    BP: 316.2°C at 760 mmHg
    FP: 145°C
    Grade: Pharmaceutical Grade
    Appearance: White Powder
    Usage: Rivastigmine Tartrate is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson’s disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting.

    Description:

    Rivastigmine (sold under the trade name Exelon) is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson’s disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting.

    Rivastigmine Tartrate is rivastigmine Alzheimer’s disease drugs, rivastigmine is physostigmine derivative by Novartis for the first time successfully developed the trade name Exelon (exelon), a molecule with there carbamate structure, is a kind of amino acid of selective cerebral cholinesterase inhibitor, can also inhibit the acetylcholinesterase and butyrylcholinesterase, cholinergic neurons by delaying the release of acetylcholine degradation and energy promoting cholinergic nerve conduction, can improve cognitive function disorders mediated by cholinergic, thereby improving the cognitive function of Alzheimer’s disease patients.

    Application:

    Rivastigmine improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical that is important for the processes of memory, thinking, and reasoning. People with dementia usually have lower levels of this chemical.
    Rivastigmine is used to treat mild to moderate dementia caused by Alzheimer’s or Parkinson’s disease.
    Rivastigmine may also be used for purposes not listed in this medication guide.
    Rivastigmine Tartrate plasma protein binding is weak, easily through the blood-brain barrier, which has a high degree of brain selectivity. It not only selectively acts on the most easily affected cerebral cortex and hippocampus, but also preferentially inhibits the dominant subtype of AChE in the brain, resulting in a reduction in the efficacy of peripheral cholinergic side effects. Rivastigmine in vivo half-life is short and long duration of action. Unlike tacrine, this product in the hippocampus and cortex of G1 enzyme inhibitory effect is stronger. Clinic for the treatment of mild to moderate Alzheimer-type dementia, or Alzheimer’s disease can be suspected Alzheimer’s disease clinically.

    Pathological changes in Alzheimer’s disease mainly involve the cholinergic nerve pathways from the basal forebrain to the cerebral cortex and hippocampus. These pathways are known to be related to attention, learning ability, memory, and other cognitive processes.
    Carbamate tartrate is a carbamate-selective acetylcholinesterase inhibitor that promotes cholinergic nerve conduction by delaying the function of complete cholinergic neurons to release the release of acetylcholine. The results of animal experiments showed that valacridine tartrate could selectively enhance the effect of acetylcholine in cerebral cortex and hippocampus.
    Therefore, Aisi can improve Alzheimer’s disease in patients with cholinergic-mediated cognitive dysfunction. In addition, cholinesterase inhibitors can slow the formation of amyloid b-amyloid precursor protein (APP) fragments. Amyloid plaque is Alzheimer’s disease tartaric acid rivastigmine by the target enzyme into a covalent complex and the latter temporarily lost activity.

    The activity of acetylcholinesterase in cerebrospinal fluid (CSF) decreased by nearly 40% within 1.5 hours after 3 mg of human administration. After the drug reaches its maximum inhibitory effect, the enzyme activity is restored to the basal level for approximately 9 hours. The inhibition of acetylcholinesterase in ruthenate tartrate in patients with Alzheimer’s disease was dose-dependent, with a maximum test dose of 6 mg twice daily.

    Dosage:

    The dosage of Exelon to treat Alzheimer’s Disease is 6-12 mg/day, given twice-a-day. The dose to treat Parkinson’s Disease is 3-12 mg/day, given twice-a-day. Exelon may interact with atropine, belladonna, clidinium, dicyclomine, glycopyrrolate, hyoscyamine, mepenzolate, methantheline, methscopolamine, propantheline, or scopolamine. Tell your doctor all medications you are taking. During pregnancy, this medication should be used only when prescribed by a doctor. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

    COA:

    Appearance A white to off-white hygroscopic crystalline powder
    Identification Should conform
    Solubility Should conform
    Specefic Rotation +10°~+14°(in 5mg/ml of water)
    Water NMT3.0%
    Heavy Metals NMT0.002%
    Limit of Free Phosphate NMT0.1%
    Limit of Sodium NMT0.2%
    Limit of chloride NMT0.2%
    Microbial Limits Test Should conform
    Related substances Should conform
    Residual Solvents should conform
    Assay 98.0%~102.0%

    Our service

    1.100% reshipment policy is our business basic.100% reshipment immediately if your parcel stays Customs for 4 days and doesn’t get updated.
    2.Total refund for 15 days of dissatisfaction with quality.
    3.We can provide free samples.
    4.We have a special packing ,It can be easily passed through the customs.It will be more safe.
    5.Our company have a long term cooperate with DHL.EMS.Fedex and so on .It can be sent to your hand more quickly. Parcel photo should be offered within 12hours after receiving your steroid payment.
    6.If you have a chance to come to China. I can show you our lab.
    7.Our company has WU, MG, TT, and Bitcoin payment ways in advance.You can pay 95% for the peptides cost at first for order, the rest can offer us in your next order;

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