Top Quality Pharmaceutical Raw White Powder Trazodone Hydrochloride
Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.
Product details:
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Product name |
Trazodone hydrochloride |
|
Other name |
2-chloro-3-pyridino |
|
Synonyms |
TRAZODONE HCL;TRAZODONE HYDROCHLORIDE;)-onehcl;2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2h;af1161;kb-831;molipaxin;pragmazone |
|
CAS register number |
25332-39-2 |
|
EINECS |
246-855-5 |
|
Product Categories |
Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;ANAHIST |
|
Molecular formula |
C19H23Cl2N5O |
|
Molecular weight |
408.32 |
| Molecular structure |
 |
|
Melting point |
223-226°C |
|
Solubility |
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 mg/mL |
|
Water Solubility |
Soluble at 25mg/ml in methanol. Also soluble in 0.1M HCl or DMSO |
|
Assay |
99% |
|
Appearence |
White to off-white powder |
|
Usage |
Antidepressant |
Description:
Trazodone (sold under many brand names worldwide is an antidepressant of the serotonin antagonist and reuptake inhibitor (SARI) class. It is a phenylpiperazine compound. Trazodone also has anti-anxiety (anxiolytic) and sleep-inducing (hypnotic) effects.Its side-effect profile and potential toxicity are considerably different from those of the original antidepressants (i.e., the monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs)).
Triazolopyridine Hydrochloride Antidepressants are used to treat various types of depression and anxiety disorders with depressive symptoms as well as mood disorders after withdrawal from drug dependence. Similar to the role of tricyclic and MAOI, clinically available for the treatment of depression, refractory depression in patients with other antidepressant therapy ineffective, the FDA is often effective. Can also be used to treat anxiety, more suitable for the treatment of senile depression or patients with heart disease. This product is benzene piperazine propyl derivative, its chemical structure with the tricyclic or tetracyclic antidepressants has nothing to do.
Trazodone Hydrochloride belongs to the hydrochloride salt form of trazodone with antidepressant and sedative activities, which is primarily used in the treatment of major depression. It serves as a serotonin uptake inhibitor that is effective for patients suffering from major depressive disorders and other subsets of depressive disorders, which is especially helpful for geriatric patients with severe agitation and certain depressive disorders associated with insomnia and anxiety since it has proved that trazodone also has anti-anxiety (anxiolytic) and sleep-inducing (hypnotic) effects. Besides, it is often prescribed as a sedative that is used for the treatment of panic attacks, aggressive behavior, agoraphobia, and cocaine withdrawal in combination with other drugs. Trazodone Hydrochloride is an oral drug that functions by affecting the balance of chemicals (neurotransmitters) within the brain that nerves use to communicate with (stimulate) each other.
Application:
Trazodone hydrochloride is indicated for the treatment of depression. The efficacy of trazodone hydrochloride has been demonstrated in both inpatient and outpatient settings and for depressed patients with and without prominent anxiety. The depressive illness of patients studied corresponds to the Major Depressive Episode criteria of the American Psychiatric Association’s Diagnostic and Statistical Manual, III1. Major Depressive Episode implies a prominent and relatively persistent (nearly every day for at least two weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least four of the following eight symptoms: change in appetite, change in sleep, psychomotor agitation or retardation, loss of interest in usual activities or decrease in sexual drive, increased fatigability, feelings of guilt or worthlessness, slowed thinking or impaired concentration, and suicidal ideation or attempts.
Trazodone hydrochloride is a hydrochloride form of trazodone, which has antidepressant and sedative effects and is mainly used to treat severe depression. It as serotonin uptake inhibitor, in patients with severe depression and other depressive disorders are effective, for its severe concussion associated with insomnia and anxiety, and some elderly patients with depressive disorder is particularly useful, because it has been proven that letrozole ketone has anti-anxiety (anti-anxiety) and sleep inducing (hypnosis) effect. In addition, it is often used as a sedative used to treat panic attacks, aggressive behavior, square phobia and cocaine withdrawal combined with other drugs. Triazolone hydrochloride is an oral drug that works by affecting the balance of chemicals in the brain (neurotransmitters) in the brain.
Benefits and Effects:
1) Trazodone hydrochloride is an antidepressant medicine. It affects chemicals in the brain that may be unbalanced in people with depression.
2) Trazodone hydrochloride is used to treat major depressive disorder.
Dosage:
Immediate-release tablets:
Initial dose: 150 mg per day in divided doses.
Maintenance dose: May be increased by 50 mg per day every 3 to 4 days. The maximum dose for outpatients usually should not exceed 400 mg per day in divided doses. Inpatients may be given up to but not in excess of 600 mg per day in divided doses.
Trazodone should be taken shortly after a meal or light snack.
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