Top Quality Anti-Inflammatory Pharmaceutical Raw Powder Pirfenidone CAS 53179-13
Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.
Product details:
Product Name: Pirfenidone
Synonyms: amr-69
CAS: 53179-13-8
MF: C12H11NO
MW: 185.22
mp: 96-97°C
storage temp: Store at RT
solubility DMSO: ≥10 mg/mL, soluble
appearance: Off-White Solid
Description:
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF – beta – 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF – beta – 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice.
Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
Application:
pirfenidone is an anti-inflammatory drug used to treat idiopathic pulmonary fibrosis.Antifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation. Regulates cytokine levels following oral administration in vivo.Potent scavenger of free radicals and inhibitor of lipid peroxidation.Pirfenidone inhibits collagen production and fibroblast proliferation. It has shown antifibrotic and anti-inflammatory properties in variety of animal models of pulmonary fibrosis, and in clinical trials.
COA:
Product name |
Pirfenidone |
batch No. |
1407101 |
CAS No. |
53179-13-8
|
Quantity |
2 kg |
Manufacture Date |
2018.3.26 |
Report Date |
2018.04.09 |
Expiry Date |
2018.05 |
Based on test |
Factory standard |
Result of Analysis |
Items |
Specifications |
Results |
Appearance |
White or almost white crystalline powder |
Meets the requirements |
Identification |
Meets the requirements |
Meets the requirements |
Melting point |
106ºC-108ºC |
107.3ºC-108ºC |
Water (K.F) |
Not more than 0.5% |
0.09% |
2-hydroxy-5-picoline |
Not more than 0.15% |
None |
Any other unspecified |
Not more than 0.1% |
0.03% |
Total impurity |
Not more than 0.5% |
0.05% |
Bromobenzene |
Not more than 0.036% |
0.01% |
Ethyl acetate |
Not more than 0.5% |
None |
Heavy metal |
Not more than 20ppm |
Less than 20ppm |
R0l |
Not more than 0.1% |
Less than 0.1% |
Assay |
Not less than 98.0% |
99.5% |
Conclusion |
Comply with the requirements. |
Our service
1.100% reshipment policy is our business basic.100% reshipment immediately if your parcel stays Customs for 4 days and doesn’t get updated.
2.Total refund for 15 days of dissatisfaction with quality.
3.We can provide free samples.
4.We have a special packing ,It can be easily passed through the customs.It will be more safe.
5.Our company have a long term cooperate with DHL.EMS.Fedex and so on .It can be sent to your hand more quickly. Parcel photo should be offered within 12hours after receiving your steroid payment.
6.If you have a chance to come to China. I can show you our lab.
7.Our company has WU, MG, TT, and Bitcoin payment ways in advance.You can pay 95% for the peptides cost at first for order, the rest can offer us in your next order;
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