Top Quality 99.5% USP Standard Pharmaceutical Raw Powder Clobetasol propionate 25122-46-7
Product Name: |
Clobetasol propionate |
Synonyms: |
17-propionate;cgp9555;clobesol |
CAS: |
25122-46-7 |
MF: |
C25H32ClFO5 |
MW: |
466.97 |
EINECS: |
246-634-3 |
Product Categories: |
Organics;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pharmaceutical intermediate;TORADOL;Hormone Drugs;Halogenated Heterocycles ,Pyrazines ,Pyrans |
Melting point |
195.5-1970C |
storage temp. |
-20°C Freezer |
CAS DataBase Reference |
25122-46-7(CAS DataBase Reference) |
Hazard Codes |
Xi,T |
Risk Statements |
36/37/38-62-53-48/20/21-61 |
Safety Statements |
26-36-45-36/37-53 |
Chemical Properties |
White Crystalline Powder |
Usage |
For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp. |
Usage |
Topical corticosteroid. Glucocorticoid; anti-inflammatory |
Abstract
Clobetasol propionate is part of a group of drugs known as glucocorticoids, which are a type of corticosteroid (or “steroid” for short). Although glucocorticoids have numerous effects in the body, they are used mostly for their anti-inflammatory or immune-suppressing properties. Clobetasol propionate works for most conditions by decreasing inflammation or suppressing an overactive immune system.
Clobetasol propionate is a corticosteroid of synthetic steroid used to treat various skin disorders including inflammation, itching, herpes labialis, eczema, psoriasis and lichen sclerosus.
Clobetasol propionate is also highly effective for contact dermatitis caused by exposure to poison ivy/oak and auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).
Clobetasol propionate is used as first-line treatment for both acute and chronic GVHD of the skin.
Brief Introdution of Clobetasol propionate:
Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available.
It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus (auto immune skin nodules).
Medical Usage of Clobetasol propionate:
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
Clobetasol propionate for synthetic efficient local external use sugar cortical hormone drugs. With strong anti-inflammatory, resistance to itch and capillary shrinkage effect, its anti-inflammatory effects of about 112.5 times of hydrocortisone sodium, betamethasone dipropionate ramification 2.3 times, fluocinolone 18.7 times. At the same time a suppression of mitosis Use, can effectively penetrate into skin cutin layer.
As a type of steroid that is applied to the skin, clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. The solution are used for scalp problems, the foam is used for mild to moderate plaque psoriasis, the cream, lotion, and spray are used for moderate to severe plaque psoriasis, and the foam and shampoo are used for moderate to severe scalp psoriasis.