Pharmaceutical Raw Materials Sex Enhancement Series Avanafil for Muscle Gain 330784-47-9
Abstract
CAS:330784-47-9
MF:C23H26ClN7O3
MW:483.95
Melting point:150-152°C
Density 1.372
storage temp. Refrigerator
Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
Store: Store at room temperature away from moisture, heat, and light
Description:
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil is known by the trademark names and Spedra and was developed by Vivus Inc. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes..
Applications:
Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).
COA :
Test Items |
Specification |
Test Results |
Description |
White or almost white crystalline powder |
White crystalline powder |
Melting Point |
191.0~193.0ºC |
192ºC |
Loss of drying |
≤1.0% |
0.5% |
Heavy Metal |
≤20ppm |
15ppm |
TLC |
Only one spot |
Only one spot |
Assay |
≥99.5% |
99.91% |
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